Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF2S2

Gene Name

eukaryotic translation initiation factor 2 subunit beta

Gene ID

8894

Gene Synonyms

eIF-2-beta; EIF2; EIF2B; EIF2beta; PPP1R67

ORF Size

1002 bp

RefSeq#

BC000461

Gene Description

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

UniGene ID

Hs.429180

HGNC ID

HGNC:3266