Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HSD17B6

Gene Name

hydroxysteroid 17-beta dehydrogenase 6

Gene ID

8630

Gene Synonyms

HSE; RODH; SDR9C6

ORF Size

954 bp

RefSeq#

BC020710

Gene Description

HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

UniGene ID

Hs.524513

HGNC ID

HGNC:23316