AAV with ApoE/hAAT1 promoter driven mCitrine

This AAV expresses mCitrine driven by a liver ApoE/hAAT1 promoter.

The ApoE/AAT1 chimeric promoter consists of the core promoter from human alpha-1-antitrypsin gene (also known as hAAT1, SERPINA1, A1A, A1AT, AAT, or alpha1AT) and the enhancer/hepatic locus control region (HCR) from the ApoE gene. The ApoE-hAAT1 chimeric promoter is about 0.7Kb and is used for driving gene expression in hepatocytes

mCitrine, like Venus, is derived from YFP, with increased brightness and stability. mCitrine has an Excitation/Emission spectrum of 516nm/529nm which is almost identical to that of EYFP, Venus and Topaz.